Mathematical modeling of Friedreich’s ataxia – a genetic neuro-muscular degenerative condition

Author:
SWASTI WAGH1 and D.K. WAGH2
Affiliation:

1M.Sc. Applied Mathematics from G.S. Institute of Tech. and Sc., Indore, M.P., India
2Ph.D., Retired Prof. of Mathematics from G.S. Institute of Tech. and Sc. ,Indore, M.P., India

Corresponding Author Swasti Wagh :Email; swastiwagh@gmail.com

Keyword:
Friedreich’s Ataxia, Stochastic matrix, Probability vector, Fixed point
Issue Date:
February, 2017
Abstract:

In this paper we propose a mathematical model of Friedreich’s Ataxia (FA) – a genetic neuro-muscular degenerative condition which causes imbalance, in-coordination and jerky limb movements. These continue to increase till patient loses independence and becomes wheelchair bound. Currently Friedreich’s Ataxia (FA) is not considered an important health problem because of its relatively low prevalence in the general population. However with improvement in health care diagnosis and delivery provisions, more and more people with Friedreich’s Ataxia (FA) are being diagnosed and surviving. This means that its incidence and prevalence is bound to change. We have used a mathematical model to estimate generational increase in the number of patients and carriers with FA. The results portray a scary picture and hence demand measures to take it more seriously by health care providers.

Pages:
66-70
ISSN:
2319-8044 (Online) - 2231-346X (Print)
Source:
DOI:
http://dx.doi.org/10.22147/jusps-A/290203
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Copy the following to cite this article:

SWASTI WAGH1 and D.K. WAGH2, "Mathematical modeling of Friedreich’s ataxia – a genetic neuro-muscular degenerative condition", Journal of Ultra Scientist of Physical Sciences, Volume 29, Issue 2, Page Number 66-70, 2017

Copy the following to cite this URL:

SWASTI WAGH1 and D.K. WAGH2, "Mathematical modeling of Friedreich’s ataxia – a genetic neuro-muscular degenerative condition", Journal of Ultra Scientist of Physical Sciences, Volume 29, Issue 2, Page Number 66-70, 2017

Available from: https://www.ultrascientist.org/paper/761/mathematical-modeling-of-friedreichs-ataxia-a-genetic-neuro-muscular-degenerative-condition

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